Creatinine

• Creatinine is a waste byproduct of muscle metabolism where creatine phosphate in muscle is broken down.
• The creatinine clearance test is a measure of the creatinine level in the urine, used primarily to evaluate kidney function.
• With normal kidney function, the serum (blood) creatinine level should remain constant and normal. A high level of creatinine in the blood and a low clearance value in the urine will tell that the kidneys are unable to excrete creatinine in the urine efficiently. A normal reading is 97 to 137 ml/min (milliliters per minute) for a male and 88 to 128 ml/min for a female.
• High creatinine clearance values can be caused by strenuous exercise, pregnancy and muscle injuries.

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